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Thymic Function Research
Khavinson et al.
Decades of work on thymic peptide regulation of immune function.
First batch in testingCOA pending
About Thymalin
Thymalin is a regulatory peptide preparation derived from thymic tissue, originally developed at the St. Petersburg Institute of Bioregulation and Gerontology. It is a polypeptide complex rather than a single defined peptide.
Research interest centers on T-cell maturation models, immunomodulation, and pre-clinical aging studies of thymic involution. The preparation has accumulated a long Russian-language research literature.
Each lot is independently verified for aggregate purity and endotoxin (LAL kinetic chromogenic) before listing.
Identity & Specifications
Sequence
Polypeptide complex (multiple components)
Length
Mixed-component preparation
Formula
Multi-component
Mol. weight
Aggregate (1–10 kDa range)
CAS
N/A
PubChem
N/A
Purity (HPLC)
Pending
Endotoxin (LAL)
Pending
Certificate of Analysis
§ First batch in testing — results populate here once the first production lot clears independent third-party verification. The table below shows the acceptance criteria every lot must meet.
| Parameter | Method | Spec | Result |
|---|---|---|---|
| Identity | ESI-MS | Conforms | Pending |
| Purity | HPLC-UV 220 nm | ≥ 98.0% | Pending |
| Endotoxin | LAL kinetic | < 0.5 EU/mg | Pending |
| Water content | Karl Fischer | ≤ 6.0% | Pending |
| Appearance | Visual | White lyophilized cake | Pending |
Selected References
- Khavinson VK, Morozov VG. Peptides of pineal gland and thymus. Neuro Endocrinol Lett, 2003.
- Morozov VG, Khavinson VK. Natural and synthetic thymic peptides. Int J Immunopharmacol, 1997.
- Anisimov VN, Khavinson VK. Peptide bioregulators of aging. Mech Ageing Dev, 2010.
- Korkushko OV, et al. Peptide regulation of aging. Bull Exp Biol Med, 2010.
- Khavinson VK, et al. Geroprotective peptides. Springer, 2005.
Recent Research Highlights
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Immunomodulation Models
Various
Studies in pre-clinical models of T-cell maturation and immune-axis aging.
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Geroprotection Research
Various
Examined in pre-clinical aging-research paradigms.
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Comparator Compound
Various
Used as a comparator in studies of thymic peptide preparations.
⊕
3rd Party Tested
Independent lab
≥98%
HPLC Purity
+ ESI-MS
LAL
Endotoxin
LAL kinetic
§
Lot-traceable
In COA library
§ Research-Use Compliance
Laboratory research chemical / reagent — not a supplement or drug.
This compound is supplied by Crescent Bioresearch LLC for laboratory research and pre-clinical use only. It is not a drug, dietary supplement, food, or cosmetic, and has not been approved by the U.S. Food and Drug Administration for human or veterinary administration, diagnosis, treatment, or prevention of any condition.
The pharmacological, toxicological, and stability properties of this compound have not been fully studied. It must therefore be handled only by personnel trained in laboratory safety practices.
The purchaser bears sole responsibility for ensuring that all handling, storage, and intended use comply with applicable local, state, and federal regulations. Full terms are set out in the RUO Disclaimer and Terms of Service.
