2019
Cellular Redox Biology
Forman et al.
Comprehensive reviews of GSH in cellular redox homeostasis.
First batch in testingCOA pending
About Glutathione
Glutathione (GSH) is the dominant low-molecular-weight thiol in mammalian cells and a central player in redox biology. Crescent supplies reduced glutathione in lyophilized form at 1,500 mg per vial.
Research interest spans oxidative-stress models, hepatic detoxification pathways, and conjugation chemistry (glutathione-S-transferase substrates). GSH is one of the most-studied cellular antioxidants and a foundational tool compound in redox-biology research.
Each lot is independently verified for purity (HPLC) and endotoxin (LAL kinetic chromogenic) before listing. Glutathione is air-sensitive — store sealed and protected from light.
Identity & Specifications
Sequence
γ-Glu-Cys-Gly
Length
3 residues
Formula
C₁₀H₁₇N₃O₆S
Mol. weight
307.32 g/mol
CAS
70-18-8
PubChem
124886
Purity (HPLC)
Pending
Endotoxin (LAL)
Pending
Certificate of Analysis
§ First batch in testing — results populate here once the first production lot clears independent third-party verification. The table below shows the acceptance criteria every lot must meet.
| Parameter | Method | Spec | Result |
|---|---|---|---|
| Identity | ESI-MS | Conforms | Pending |
| Purity | HPLC-UV 220 nm | ≥ 98.0% | Pending |
| Endotoxin | LAL kinetic | < 0.5 EU/mg | Pending |
| Water content | Karl Fischer | ≤ 6.0% | Pending |
| Appearance | Visual | White lyophilized cake | Pending |
Selected References
- Meister A, Anderson ME. Glutathione. Annu Rev Biochem, 1983.
- Lu SC. Glutathione synthesis. Biochim Biophys Acta, 2013.
- Forman HJ, et al. Glutathione: overview of its protective roles. Mol Aspects Med, 2009.
- Townsend DM, Tew KD. The role of glutathione-S-transferase in anti-cancer drug resistance. Oncogene, 2003.
- Pompella A, et al. The changing faces of glutathione. Biochem Pharmacol, 2003.
Recent Research Highlights
2013
Liver Detoxification
Lu · Mol Aspects Med
Reviewed GSH-mediated detoxification pathways and Phase II conjugation chemistry.
2009
Oxidative Stress Markers
Townsend et al.
Described GSH-S-transferase reaction substrates and assays in oxidative-stress research.
—
Foundational Glutathione Research
Meister
Decades of foundational work on glutathione biochemistry.
⊕
3rd Party Tested
Independent lab
≥98%
HPLC Purity
+ ESI-MS
LAL
Endotoxin
LAL kinetic
§
Lot-traceable
In COA library
§ Research-Use Compliance
Laboratory research chemical / reagent — not a supplement or drug.
This compound is supplied by Crescent Bioresearch LLC for laboratory research and pre-clinical use only. It is not a drug, dietary supplement, food, or cosmetic, and has not been approved by the U.S. Food and Drug Administration for human or veterinary administration, diagnosis, treatment, or prevention of any condition.
The pharmacological, toxicological, and stability properties of this compound have not been fully studied. It must therefore be handled only by personnel trained in laboratory safety practices.
The purchaser bears sole responsibility for ensuring that all handling, storage, and intended use comply with applicable local, state, and federal regulations. Full terms are set out in the RUO Disclaimer and Terms of Service.
